Exploring Polynucleotides: A New Type of Regenerative Treatment

by | Oct 31, 2023 | Treatments | 0 comments

In the ever-evolving world of medical aesthetics, we are constantly seeking innovative ways to provide natural and lasting results for you. One such advancement in regenerative medicine is using polynucleotides, a promising treatment option that aligns perfectly with the philosophy of our medical-led aesthetic and skincare clinic in Ringwood, Hampshire. In this blog post, we’ll explore what polynucleotides are and how they can help you.


What Are Polynucleotides?

Polynucleotides, often abbreviated as PNs, are biological molecules consisting of long chains of nucleotides. Nucleotides are the building blocks of DNA and RNA, and they play a fundamental role in cell function and repair.

In aesthetic medicine, polynucleotides are derived from natural sources like salmon or trout DNA. They are intensely purified and then used as a powerful tool to enhance skin health.

What Can Polynucleotides Treat?

    • Skin Rejuvenation: Polynucleotides are well-known for stimulating collagen, elastin and intrinsic hyaluronic acid production, producing firmer, plumper skin with fewer visible lines and wrinkles.
    • Scar Reduction: They aid in minimising the appearance of scars, including acne and surgical or traumatic scars. As soon as a few weeks after surgery, polynucleotides can accelerate wound healing, improve blood flow to the area, reduce inflammation and redness, and produce more healthy collagen. They can also be used on older and acne scars to enhance skin texture and volume deficit.
    • Hydration and Radiance: Polynucleotides improve skin hydration and boost radiance, creating a natural, healthy glow.
    • Thinning hair or hair loss: Due to their ability to improve the function of cells and stimulate blood flow, this treatment is a powerful tool for patients with thinning hair or areas of hair loss. Studies have shown that following a course of treatments, hair thickness and density improved, and hair shedding significantly reduced.

Polynucleotides can be used anywhere on the body where you have concerns, but commonly treated areas include the face, specifically under the eyes and around the lips, neck, decolletage and scalp.

The Treatment Itself

Polynucleotide treatments can be administered using either needles or cannulas (blunt, flexible needles), depending on the specific requirements of each patient. Needles are typically used for precise targeting of wrinkles or scars. At the same time, cannulas are favoured for more extensive treatments or broader areas, as they reduce the risk of bruising and trauma to blood vessels. Perfect if you want to minimise the downtime!

The treatment can sting in some areas, so we will always apply a good layer of topical numbing cream before your treatment. Once we start, the treatment will take around 15-30 minutes, depending on the area treated.

After polynucleotide treatments, you may experience minor swelling, bumps, redness, or bruising. However, these side effects are usually temporary and can be concealed with makeup. Because of the downtime, we advise that you have this treatment at least two to three weeks before any big event, such as a wedding or party, to allow all side effects to resolve fully.

Treatments That Work Well With Polynucleoides

To maximise the benefits of polynucleotide treatments and achieve the natural outcomes your clinic specialises in, consider combining them with the following procedures:

    1. Microneedling: Our microneedling treatment is a fantastic collagen-stimulating treatment in its own right, and we can use the power of polynucleotides to enhance the results even further. We recommend a combined course, alternating microneedling and polynucleotide treatments each month.
    2. Profhilo: Combining Profhilo, a hyaluronic acid treatment, with PNs can provide deep hydration and overall skin improvement. Perfect if you are looking for that more immediate glow but want a longer-term benefit.
    3. Morpheus 8: This radiofrequency microneedling procedure can be a powerful complement to PNs, as it tightens the skin and improves texture, so you benefit the skin and sculpt the tissues simultaneously. The best pairing, in our opinion!

Recommended Treatment Plan

For optimal results, consider recommending a treatment course of four sessions, spaced four weeks apart, followed by maintenance treatments every 6-12 months. This approach ensures that you experience gradual and long-lasting improvements in their skin while maintaining its natural appearance.


We offer polynucleotide treatments for £250 per session or £650 for 3 treatments. You can book a consultation or treatment via our online booking page or contact us for more information.

In Summary

Polynucleotides are a valuable addition to our wide selection of options. Their ability to rejuvenate the skin, reduce wrinkles, and enhance overall skin health perfectly complements our commitment to providing natural and long-lasting results. By combining polynucleotides with other treatments and following a recommended treatment plan, we can help you achieve the radiant, youthful skin you desire.

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